摘要
Abstract
Objective To discuss the related factors of patients with type 2 diabetes melitus (T2DM) and non-alcoholic fatty liver disease (NAFLD) and analyzed the relationship with insulin resistance. Method 164 patients with T2DM were divided into observation group (108 cases) and control group (138 cases) according to whether with NAFLD, and then gender, age, BMI, WHR, duration of diabetes, ALT, AST, TG, TC, LDL, HDL, HbAlc, FBG, FINS and HOMA-IR were contrasted between two groups, and positive factor were analyzed with Logistic regression analysis, and liver were detected with ultrasound, then the relationship between ultrasound score of liver and HOMA-IR were analyzed. Result There were no signiifcant difference between two groups in sex, age, FBG, FINS, HDL (P > 0.05);comparison of signiifcant differences in BMI, WHR, duration of diabetes, ALT, AST, TC, TG, LDL, HbAlc, HOMA-IR (P < 0.01). Logistic regression analysis showed that, BMI, TG, LDL, HbAlc and HOMA-IR were independent risk factors are of T2DM patients with NAFLD (P<0.05 or P<0.01). Conclusion HOMA-IR and NAFLD ultrasound scores show a signiifcant positive correlation, results suggest that HOMA-IR can relfect T2MD risk patients with NAFLD, and help to assess the patient's condition.关键词
2型糖尿病/非酒精性脂肪性肝病/相关因素/胰岛素抵抗Key words
Type 2 diabetes melitus/Non-alcoholic fatty liver disease/Related factor/Insulin resistance
