摘要
Abstract
ObjectiveTo investigate the inlfuence of laparoscopic-assisted D2 resection on distal advanced gastric cancer patients with gastrin family indexes.Method30 patients with distal advanced gastric cancer who were treated in our hospital from April 2012 to May 2013 were chose for the study and were randomly divided into control group and observation group, 15 cases in each group. Control group were treated with conventional open D2 resection. observation group were treated with laparoscopic-assisted D2 resection, observed and recorded the two groups of general information (operative time, blood loss, number of lymph node dissection, recovery of gastrointestinal function time and hospital stay), hematological indices after 7 days, 7 days preoperative and postoperative gastrin family indexes [general adaptation syndrome (GAS), cholecystokinin (CCK) and human motilin (MTL)] and postoperative complications.ResultThe differences of operative time and number of lymph node dissection between the two groups were not signiifcant (P>0.05); the blood loss, gastrointestinal function recovery time, hospital stay of patients in the observation group were less than control group (P<0.01). The differences of albumin and white blood cell counts between the two groups were not signiifcantly (P>0.05); the albumin, hemoglobin levels before surgury of the observation group were higher, the C reactive protein was lower than control group (P<0.05 orP<0.01); the differences of GAS, MTL, CCK levels before surgery between the two groups were not statistically signiifcant (P>0.05);the GAS, MTL after 7 days of the two groups were signiifcantly lower than the preoperative (P<0.05), the CCK before surgery were signiifcantly higher (P<0.05), but GAS, MTL levels of patients in observation group were signiifcantly higher (P<0.05), the CCK level was signiifcantly lower than control group (P<0.05). The complication rate of observation group was 20.0% (3/15), control group was 33.3% (5/15), the difference was not statistically significant (P>0.05).ConclusionCompared with conventional D2 resection, the radical gastrin family indexes and the treatment of hematological distal lfuctuations of advanced gastric cancer of laparoscopic-assisted D2 resection are relatively smaller, it is more effective to shorten the operation time, recovery time of gastrointestinal function, hospital stay time, increase the number of lymph node dissection, reduce blood loss, and will not increase the incidence of postoperative complications, safe and effective, worthy of clinical application.关键词
远端进展期胃癌/腹腔镜辅助D2根治术/血液学指标/胃泌素族Key words
Distal advanced gastric cancer/Laparoscopic-assisted D2 resection/Hematology/Gastrin family
