中国癌症防治杂志Issue(3)：280-283,284,5.DOI:10.3969/j.issn.1674-5671.2014.03.13
超声检查与血清CA125检测在卵巢恶性肿瘤诊断中的价值
Diagnostic value of ultrasound and serum levels of CA125 in ovarian cance
摘要
Abstract
Objective To explore the value of ultrasound and serum levels of CA125 in ovarian cancer diagnosis. Methods A consecutive series of 113 patients with ovarian tumor treated between October 2012 and December 2013 were analyzed. Patients included 53 cases of malignancy and 60 cases of benign tumors; all were diagnosed based on ultrasound and serum levels of CA125 one week before surgery,and then definitively diagnosed based on postoperative pathology. To adjust for baseline differences between the two groups, propensity-score matching was used to generate 34 pairs of patients. Results Serum CA125 assay showed the following diagnostic performance:sensitivity,88.2%;specificity,61.8%,PPV,69.8%;NPV,84.0%;and accuracy,75.0%. The corresponding values for ultrasound were 85.3%,88.2%,87.9%,85.7% and 86.8%. The corresponding values for the combination of serum CA125 assay and ultrasound were 94.1%,64.7%,72.7%,91.7% and 79.4%. Ultrasound alone showed significantly higher specificity than either serum CA125 alone or the combination of both methods (P<0.05). However,sensitivity,PPV,NPV and accuracy were similar across all three diagnostic methods(P>0.05). Conclusion Combining ultrasound with serum CA125 assay does not improve diagnostic accuracy.关键词
卵巢肿瘤/超声检查/CA125检测Key words
Ovarian neoplasm/Ultrasound/Serum CA125 assay分类
医药卫生引用本文复制引用
张俊,马燕,马海英,陈冬秀,李晶晶..超声检查与血清CA125检测在卵巢恶性肿瘤诊断中的价值[J].中国癌症防治杂志,2014,(3):280-283,284,5.基金项目
广西研究生教育创新计划项目 （）
