中国癌症防治杂志Issue(3)：206-208,209,4.DOI:10.3969/j.issn.1674-5671.2015.03.14
MDCT动态增强扫描测量肝癌与膈肌交界面弓弦比对膈肌侵犯的诊断价值
MDCT measurement of the ratio of arch distance to maximum tumor diameter as a method for detecting diaphragmatic invasion in hepatocellular carcinoma
摘要
Abstract
Objective To develop a noninvasive technique for evaluating diaphragmatic invasion using routine preoperative dynamic enhanced MDCT. Methods This retrospective study involved 90 patients with histopathologically proven hepatocellular carcinoma and in whom multiphasic MDCT indicated that the tumor was close to the diaphragm. The length of the interface between the primary tumor and neighboring structures (arch distance)as well as the maximum tumor diameter were measured from the images,and the ratio of arch distance to maximum tumor diameter was calculated. Ratios were analyzed using receiver operating characteristic(ROC)curves. Results In 3 phases of dynamic contrast-enhanced MDCT (plain,arterial and venous),the ratio of arch distance to maximum tumor diameter was significantly higher for lesions showing diaphragmatic invasion than for those not showing diaphragmatic invasion. The area under the ROC curve for diagnosing diaphragmatic invasion was 0.893 in the venous phase,0.769 in the arterial phase and 0.814 in the plain phase.With a cut-off of 1.07,using the technique in the venous phase allowed diagnosis of diaphragmatic invasion with a sensitivity of 89.2% and specificity of 84.9%. Conclusion Measurement of the ratio of arch distance to maximum tumor diameter in the venous phase of MDCT is a simple and effective noninvasive technique for detecting diaphragmatic invasion.关键词
肝肿瘤/计算机体层摄影/膈肌/膈肌侵犯/诊断Key words
Liver neoplasm/Computed tomography/Diaphragm/Diaphragmatic invasion/Diagnosis分类
医药卫生引用本文复制引用
左阳,苏丹柯,赖少侣,刘丽东,罗宁斌,金观桥,刘宇..MDCT动态增强扫描测量肝癌与膈肌交界面弓弦比对膈肌侵犯的诊断价值[J].中国癌症防治杂志,2015,(3):206-208,209,4.基金项目
广西科学研究与技术开发计划资助项目（桂科攻1355005-3-1）；广西医疗卫生适宜技术研究与开发资助项目 （）
