中国医学装备Issue(10)：49-52,53,5.DOI:10.3969/J.ISSN.1672-8270.2014.10.017
体素内不一致运动磁共振成像后处理中单指数和双指数模型的比较
Comparison of mono-exponential and bi-exponential model in IVIM post-processing
王丽雯 1谢晟 1王蕾 1常飞燕 1王武1
作者信息
- 1. 中日友好医院放射诊断科 北京 100029
- 折叠
摘要
Abstract
Objective: To compare the mono-exponential and bi-exponential model in the determination of diffusion parameters in the post-processing of intravoxel incoherent motion MR imaging (IVIM). Methods: Thirty patients without brain parenchyma lesions and 30 patients with cerebral metastases underwent IVIM and Perfusion-weighted imaging scanning. The mono-exponential model and the bi-exponential model were used to measure the slow ADC, fast ADC and Fraction of Fast ADC for ROIs in the brain tissue.Compare with the two models. And contrast this with the infusion. Results: Paired t-test showed statistical significant difference of the measures including slow ADC, fast ADC and Ff between the two models(t=23.268, t=-5.927, t=-17.052;P<0.05). The Bland-Altman plots for the measures of mono-exponential model and bi-exponential model indicated good consistency. Measures of the Mono-exponential model had lower overall variability than those of biexponential model (slow ADC 19%VS. 42%, fast ADC 69%VS. 171%, Ff 43%VS. 21%). Fast ADC and Ff of the Mono-exponential model showed significant relationship with CBF and CBV. Conclusion:There is good consistency of the measures between the mono-exponential and bi-exponential model. Mono-exponential model is superior to the bi-exponential model because of low variability, therefore is more suitable for clinical application.关键词
核磁共振/体素内不一致运动核磁共振成像/单指数模型/双指数模型/表观扩散系数Key words
Magnetic resonance imaging/Intravoxel incoherent motion MR imaging/Mono-exponential model/Bi-exponential model/Apparent Diffusion Coefficient分类
医药卫生引用本文复制引用
王丽雯,谢晟,王蕾,常飞燕,王武..体素内不一致运动磁共振成像后处理中单指数和双指数模型的比较[J].中国医学装备,2014,(10):49-52,53,5.
