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体部伽玛刀治疗门静脉主干癌栓疗效观察

齐文杰 康静波 李启亮 朱奇 蔡昌兰

中国医学装备Issue(11):122-123,124,3.
中国医学装备Issue(11):122-123,124,3.DOI:10.3969/J.ISSN.1672-8270.2014.11.045

体部伽玛刀治疗门静脉主干癌栓疗效观察

Observation of clinical therapeutic effectiveness of body gamma knife in treating the main portal vein tumor thrombus in hepatocellular carcinoma

齐文杰 1康静波 1李启亮 1朱奇 1蔡昌兰1

作者信息

  • 1. 海军总医院肿瘤诊疗中心 北京 100048
  • 折叠

摘要

Abstract

Objective:To investigate the clinical therapeutic effectiveness of body gamma knife in treating the portal vein tumor thrombus (PVTT) in patients with primary hepatocellular carcinoma.Methods: From August 2006 to June 2010, the total of 52 patients with PVTT of unresectable hepatocellular carcinoma were treated by body gamma knife. The planned target volume (PTV) was encompassed by 50%~70% isodose line. The single therapeutic dose was 3.0Gy to 4.5Gy, and total dose was from 30Gy to 49.5Gy. To observe the term efficacy and survival rate of PVTT. Results: 3months after treatment, CR was 18 cases (34.62%), PR was 23 cases (44.23%), and the effective power (CR+PR) of PVTT was 78.85%. 6, 12, 24-month survival rate was 92.31%, 73.08% and 55.77%. The median survival time was 14.0 months. Conclusion: Body gamma knife is an effective method in the treatment of portal vein tumor thrombus in hepatocellular carcinoma, and can extend the survival time.

关键词

肝细胞癌/门静脉癌栓/伽玛刀

Key words

Hepatocellular carcinoma/Portal vein tumor thrombosis/Body gamma knife

分类

医药卫生

引用本文复制引用

齐文杰,康静波,李启亮,朱奇,蔡昌兰..体部伽玛刀治疗门静脉主干癌栓疗效观察[J].中国医学装备,2014,(11):122-123,124,3.

中国医学装备

OACSTPCD

1672-8270

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