中国医学装备Issue(12)：127-129,3.DOI:10.3969/J.ISSN.1672-8270.2014.12.048
乌司他丁对体外循环瓣膜置换术患者围手术期炎性细胞因子水平的影响
Research on effect of ulinastatin on patients' inflammatory factors level during cardiopulmonary bypass valve replacement surgery
何伟 1原庆会2
作者信息
- 1. 绵阳市中心医院麻醉科 四川 绵阳 621000
- 2. 绵阳市中心医院病理科 四川 绵阳 621000
- 折叠
摘要
Abstract
Objective: To analyze effect of ulinastatin on patients’ inflammatory factors level during cardiopulmonary bypass valve replacement surgery. Methods: Chosen patients accept cardiopulmonary bypass valve replacement surgery between 2011 to 2013 as research subjects, randomized to receive Ulinastatin as observation group and volume of saline as control group, testing inflammatory levels and pulmonary ventilation function difference. Results: One hour after CPB and 1h after the end of CPB, TNF-α, IL-6 level as well as A-aDO2 level of observation group were lower than control group; (2)A-aDO2 levels were positively correlated with TNF-α, IL-6 levels. Conclusion: Ulinastatin can effectively reduce cardiopulmonary bypass valve replacement surgery preoperative inflammatory cytokine levels, reducing the impact on pulmonary ventilation function, inflammatory levels and pulmonary ventilation function was negatively correlated.关键词
瓣膜置换术/乌司他丁/体外循环/炎性细胞因子Key words
Valve replacement surgery/Ulinastatin/Cardiopulmonary bypass/Inflammatory cytokine分类
医药卫生引用本文复制引用
何伟,原庆会..乌司他丁对体外循环瓣膜置换术患者围手术期炎性细胞因子水平的影响[J].中国医学装备,2014,(12):127-129,3.
