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重组人血小板生成素联合糖皮质激素和环胞素A治疗免疫性血小板减少症的研究

孔凡霞 陈晓乐 杜秋香 李楠 罗清霞 段红萍 顾海霞

中国医学装备Issue(5):36-38,3.
中国医学装备Issue(5):36-38,3.DOI:10.3969/J.ISSN.1672-8270.2015.05.011

重组人血小板生成素联合糖皮质激素和环胞素A治疗免疫性血小板减少症的研究

Recombinant human thrombopoietin combined with corticosteroids and cyclosporine A treatment reduced the effect of disease of immune platelet

孔凡霞 1陈晓乐 2杜秋香 2李楠 1罗清霞 1段红萍 1顾海霞3

作者信息

  • 1. 邯郸市第三医院药剂科 河北 邯郸 056001
  • 2. 邯郸市第三医院检验科 河北 邯郸 056001
  • 3. 邯郸市第三医院眼科 河北 邯郸 056001
  • 折叠

摘要

Abstract

Objective: To investigate the recombinant human thrombopoietin, corticosteroids, cyclosporin A combined therapy to reduce purpura 75 cases of immune thrombocytopenic. Methods: From 2011 March to 2014 January in our hospital were treated with immune thrombocytopenic purpura patients a total of 75 cases, were given the treatment of thrombopoietin, corticosteroids, cyclosporin A recombinant human, compared before and after treatment (platelet), PLT (WBC), WBC (hemoglobin) Hb changes and the total curative effect of therapy. Results:Before treatment, PLT, WBC, Hb were (14.41+2.11)×109/L, (8.92+1.01)×109/L, (119.32+9.8)g/L, respectively after treatment for (118.92+14.50)×109/L, (9.01+1.05)×109/L, (120.14+6.84) g/L, the number of platelet therapy significantly higher than before treatment (t=61.769, P=0.000), WBC, Hb before and after treatment showed no statistical significance (t=0.535, P=0.593;t=0.594, P=0.0553). The total curative effect in the treatment of treatment was 89.3%(67/75), the rate of adverse reaction was 4%. Conclusion:The combined application of recombinant human thrombopoietin, corticosteroids, cyclosporin A in the treatment of ITP curative effect is good, significantly improve the platelet count, worthy of promotion.

关键词

重组人血小板生成素/糖皮质激素/环孢素A/免疫性血小板减少性紫癜

Key words

Recombinant human thrombopoietin/Glucocorticoid/Cyclosporine A/Immune thrombocytopenic purpura

分类

医药卫生

引用本文复制引用

孔凡霞,陈晓乐,杜秋香,李楠,罗清霞,段红萍,顾海霞..重组人血小板生成素联合糖皮质激素和环胞素A治疗免疫性血小板减少症的研究[J].中国医学装备,2015,(5):36-38,3.

中国医学装备

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1672-8270

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