中国医学装备Issue(6)：112-115,4.DOI:10.3969/J.ISSN.1672-8270.2015.06.034
高血压肾功能损害患者血清中转化生长因子β1含量检测及其临床价值分析
The levels of TGF-β1 in hypertensive renal function impairment patients and its clinical value analysis
王恭 1云辉 1曾学平2
作者信息
- 1. 解放军第187医院门诊部 海南 海口 571159
- 2. 解放军第187医院输血科 海南 海口 571159
- 折叠
摘要
Abstract
Objective:To detect the levels of TGF-β1 in hypertensive renal function impairment patients and its clinical value. Methods: Primary hypertension patients with no target organs damage were enrolled in control group, primary hypertension patients with renal function stageⅠand stageⅡwere enrolled in renal function stageⅠgroup and stageⅡgroup. Serum TGF-β1 levels and renal function indices of three groups were compared. Results:There were no significant difference of serum creatinine and blood urea nitrogen of three groups(F=23.523, P<0.05);endogenous creatinine clearance rate of renal functionⅠandⅡgroups were lower than that of control group, TGF-β1 levels of renal functionⅠandⅡ groups were higher than of control group; TGF-β1 levels were negatively correlated with creatinine clearance rate. Conclusion:TGF-β1 level is an ideal index to reflect renal function for its level significantly changes in renal damage stageⅠ,Ⅱand has good correlation with Cin.关键词
高血压/肾功能损害/转化生长因子β1/内生肌酐清除率Key words
Hypertension/Renal function impairment/Transforming growth factor-β1/Endogenous creatinine clearance rate分类
医药卫生引用本文复制引用
王恭,云辉,曾学平..高血压肾功能损害患者血清中转化生长因子β1含量检测及其临床价值分析[J].中国医学装备,2015,(6):112-115,4.
