中国药业Issue(12)：29-30,2.
血清超敏C反应蛋白检测用于美托洛尔治疗心力衰竭50例疗效评价
Detecting Serum hs - CRP for Evaluating Effect of Metoprolol in Treating Heart Failure in 50 Cases
刘娜 1翟雨佳 1舒景 1苗阳 1崔欣欣 1刘志强1
作者信息
- 1. 河北省正定县人民医院，河北 石家庄 050800
- 折叠
摘要
Abstract
Objective To investigate the application of hypersensitive C reaction protein(hs - CRP)for evaluating the effect of metopro-lol in the treatment of heart failure. Methods 50 cases of heart failure treated in our hospital from December 2011 to December 2012 were selected. Before the metoprolol treatment,serum hs - CRP level was measured by using nephelometry method. After the metoprolol treatment for 6 months,the serum hs - CRP level was redetected and the efficacy was evaluated. Meanwhile 40 individuals with healthy physical examination as the control group were randomly selected for detecting serum hs - CRP level. Results The serum hs - CRP lev-el before treatment in the heart failure patients was significantly higher than that in the normal group,the difference was statistically significant( P < 0. 05);after 6 - month metoprolol treatment,the patient' s serum hs - CRP level in the patients was significantly lower than before treatment,the difference was statistically significant( P < 0. 05),but compared with the normal group,no significant difference existed( P > 0. 05). Meanwhile the curative effect of metoprolol had the correlation with serum hs - CRP level,the hs - CRP level was (0. 91 ± 0. 36)mg / L in reaching significant effect,(4. 38 ± 1. 23)mg / L in reaching effect and(9. 77 ± 3. 91)mg / L in the ineffective patients. Conclusion Detecting Hs - CRP level for evaluating the efficacy of metoprolol in the treatment of heart failure has important clinical value and deserves to be clinically promoted.关键词
超敏 C 反应蛋白/心力衰竭/美托洛尔/疗效Key words
hs - CRP/heart failure/metoprolol/effeciveness分类
医药卫生引用本文复制引用
刘娜,翟雨佳,舒景,苗阳,崔欣欣,刘志强..血清超敏C反应蛋白检测用于美托洛尔治疗心力衰竭50例疗效评价[J].中国药业,2014,(12):29-30,2.
