中国药业Issue(13)：9-10,11,3.
金丝桃素提取物稳定性考察
Stability of Hypericin Extract
摘要
Abstract
Objective To investigate the stability of hypericin extract. Methods Hypericin and pseudo-hypericin were detected by high performance liquid chromatography ( HPLC ) . The content change of hypericin and pseudohypericin in hypericin extract was used as the indicator. The effects of light, temperature and ascorbic acid on the short-term and long-term stability of hypericin extract were stud-ied. Results In the short term, the hypericin extract was more stable under the conditions of the room temperature away from light and adding ascorbic acid; the hypericin and pseudo-hypericin contents were increased within a short time and then began to decline in light;the extract stability was poor at the high temperature. Within 8 weeks, the hypericin and pseudo-hypericin contents in the hyper-icin extract were declined in varying degrees under the conditions of light at the room temperature, protected from light at the room temperature and adding ascorbic acid;but which were comparatively stable under the low temperature without light. Conclusion The hypericin extract should be stored at the low temperature without light.关键词
金丝桃素提取物/金丝桃素/伪金丝桃素/稳定性Key words
hypericin extract/hypericin/pseudo-hypericin/stability分类
医药卫生引用本文复制引用
王金林,李前琼,王晓利,何利思,张俊松,张德志..金丝桃素提取物稳定性考察[J].中国药业,2014,(13):9-10,11,3.基金项目
广东省深圳市科技局科技项目，项目编号06KJP038；深圳职业技术学院重点科研课题，项目编号08KJba019。 （）
