摘要
Abstract
Objective To investigate the efficacy of Xianlinggubao Capsule in treating thoracolumbar osteoporotic fracture to provide ref-erence for clinical treatment. Methods 108 patients with thoracolumbar osteoporotic fracture in our hospital were randomly divided into the observation group and the control group 54 cases in each group. The control group used the oral administration of alendronate com-bined with calcium carbonate D3,while the observation group was given oral Xianlinggubao capsule. After 6 months of treatment,the vi-sual analogue score(VAS),bone density examination and vertebral wedge compression index were adopted to evaluate the clinical effica-cy in the two groups and the occurrence situation of adverse reactions were observed. Results The total effective rate after treatment was 96. 30% in the observation group and 98. 15% in the control group;the VAS was(1. 68 ± 0. 91)points in the observation group and(1. 70 ± 0. 81)points in the control group;the T value of radius bone density was( - 2. 64 ± 0. 63)in the observation group and ( - 2. 41 ± 0. 57)in control group,the comparison of the above data showed no statistical differences between the two groups. The verte-bral body compression degree after treatment in the observation group was significantly greater than that in the control group( P ﹥0. 05) with statistical difference between them( P ﹤ 0. 05). The occurrence rate of adverse reactions was 7. 41% in the observation group and 24. 07% in the control group with statistically significant difference between them( P ﹤ 0. 05). Conclusion Xianlinggubao Capsule can significantly increase the bone density in the patients with thoracolumbar osteoporotic fracture and alleviate their pain with good curative effect and good security,which is worthy of clinical promotion promoted in clinic.关键词
仙灵骨葆胶囊/阿仑膦酸钠/碳酸钙D3/胸腰椎骨质疏松性骨折Key words
Xianlinggubao Capsule/alendronate/calcium carbonate D3/thoracolumbar osteoporotic fracture分类
医药卫生
