中国药业Issue(15)：27-28,29,3.
替普瑞酮联合奥美拉唑对胃良性溃疡愈合质量的影响
Influence of Teprenone Combined with Omeprazole on Healing Quality of Benign Gastric Ulcer
卢英军 1李树义 1王静1
作者信息
- 1. 河北省唐山市第九医院，河北 唐山 063000
- 折叠
摘要
Abstract
Objective To investigate influence of gastric mucosal protective agent teprenone the healing quality of benign gastric ulcer. Methods 177 patients with benign gastric ulcer were randomly divided into the control group(88 cases) and the observation group(89 cases) . The control group was given teprenone and the observation group was given omeprazole combined with teprenone. The patients were followed up for 1 year. The clinical effect, gastric ulcer healing quality, adverse reactions and recurrence were compared between two groups. Results The total effective rate in the observation group was 97. 75% , which was significantly higher than 89. 77% in the con-trol group( P ﹤ 0. 05); the S2 - stage shift rate in the observation group was 66. 29% , which was significantly higher than 27. 27% in the control group( P ﹤ 0. 05). The occurrence rate of nausea, abdominal pain, diarrhea and skin rash in the observation group was higher than that in the control group, but the bleeding rate in the observation group was lower than that in the control group, the differences had no statistically significant; the recurrence rate in the observation group was significantly lower that that in the control group( P ﹤ 0. 05). Conclusion The combination of the gastric mucosal protective agent teprenone and the proton pump inhibitor omeprazole can obviously increase the cure rate, has less adverse reactions and high safety, can apparently decrease the recurrence rate, which is worthy of clinical promotion.关键词
替普瑞酮/奥美拉唑/胃溃疡/愈合质量Key words
teprenone/omeprazole/gastric ulcer/healing quality分类
医药卫生引用本文复制引用
卢英军,李树义,王静..替普瑞酮联合奥美拉唑对胃良性溃疡愈合质量的影响[J].中国药业,2014,(15):27-28,29,3.
