摘要
Abstract
Objective To investigate the effect of Compound Shenqi Vitamin E Capsules combined with famciclovir on the immune func-tion in the patients with herpes zoster. Methods 124 cases of herpes zoster were randomly divided into the observation group( n = 62) and the control group( n = 62). The control group simultaneously applied famciclovir and intramuscular injection of interferon for continu-ous 7 d;while at the beginning the medication in the observation group was same to the control group,after drug withdrawal oral Compound Shenqi Vitamin E Capsules was given for continuous 10 d. The clinical effects and the symptom remission time were com-pared between the two groups. The levels of CD4+ T lymphocyte subsets before and after treatment in the two groups were detected by the flow cytometry. Results The total effective rate of observation group was 93. 55% ,which was higher than 77. 42% in the control group,the difference had statistical significance( P < 0. 05). The time of blister stop,crusting time,pain relief time and decrustation time in the observation group were shorter than those in the control group( P < 0. 05). The levels of CD +3 ,CD4+ and CD4+ / CD +8 in the ob-servation group were significantly higher than those in the control group,while the level of CD +8 was lower than that in the control group( P < 0. 05). The incidence rate of postherpetic neuralgia in observation group was 0. 00%(0 / 62),which was lower than 8. 06%(5 / 62)in the control group,there was statistically significant difference between the two groups( P < 0. 05). Conclusion Compound Shenqi Vtamin E Capsule combined with famciclovir in treating herpes zoster can improve the curative effect,alleviate the clinical symptoms,effectively prevent the occurrence of postherpetic neuralgia and simultaneously increase the patient’s immune function.关键词
复方参芪维E胶囊/泛昔洛韦/带状疱疹/免疫功能Key words
Compound Shenqi Vtamin E Capsule/famciclovir/shingles/immune function分类
医药卫生
