摘要
Abstract
Objective To investigate the clinical efficacy and safety of Mupirocin Ointment and Fusidic Acid Ointment in treating bac-terial infectious skin diseases. Methods 94 patients with bacterial skin infectious disease were randomly selected from the Jiangsu Provincial People' s Hospital from July 2010 to August 2013 and divided into the treatment group and the control group with 47 cases in each group. The treatment group adopted 2% Fusidic Acid Ointment for treatment,while the control group was given 2% Mupirocin Ointment for treatment. The changes of the skin lesion area and the eczema area severity index(EASI) before and after 2 courses of treatment and the differences of adverse reactions were compared between the two groups. Results The EASI scores and the pruritus scores after treat ment in the treatment group and the control group were significantly decreased compared with before treatment ( P < 0. 05);but the EASI scores and the pruritus scores in the treatment group was significantly lower than those in the control group ( P < 0. 05). The total effective rate in the treatment group was 95. 74%,which was higher than 91. 49% in the control group,but the difference was not statistically significant;the cure rate in distribution in the treatment group was higher than that in the control group,the effect distribution of the two groups had statistically significant difference,the effective distribution in the treatment group was superior to that in the control group. Conclusion Adopting 2% Fusidic Acid Ointment in treating bacterial infectious skin disease can better relieve the clinical symptoms with good clinical efficacy.关键词
莫匹罗星软膏/夫西地酸软膏/细菌感染性皮肤病/疗效Key words
Mupirocin Ointment/Fusidic Acid Ointment/bacterial infectious skin disease/curative effect分类
医药卫生
