中国药业Issue(22)：63-64,65,3.
缬沙坦胶囊制备工艺和质量控制研究
Preparation Process and Quality Control of Valsartan Capsules
危媚1
作者信息
- 1. 福建生物工程职业技术学院，福建 福州 350002
- 折叠
摘要
Abstract
Objective To study the formulation and preparation process of Valsartan Capsules,and to conduct the quality control.Methods The reference preparation formulation was introduced and its rationality was analyzed;with the items of dissolution rate, related substances,etc. as the investigation indexes,the preparation process was screened and determined. Results The formulation of reference preparation possessed the rationality and could be used as the formulation of the development product;the preparation technology by the dry granulating method was suitable,the indexes of related substances and dissolution rate in the prepared product were similar to that of the reference preparation,and the preparation characteristics met the consistency requirement of preparation quality. Conclusion The formulation of developed Valsartan Capsules is reasonable,the preparation process is suitable for the industrial production and its quality is stable.关键词
缬沙坦胶囊/制备工艺/质量控制Key words
Valsartan Capsules/preparation process/quality control分类
医药卫生引用本文复制引用
危媚..缬沙坦胶囊制备工艺和质量控制研究[J].中国药业,2014,(22):63-64,65,3.
