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重组人脑利钠肽治疗老年急性心肌梗死泵衰竭84例

赵军峰 孟淑萍 柳君 李国君 马晓鹏

中国药业Issue(3):64-64,65,2.
中国药业Issue(3):64-64,65,2.

重组人脑利钠肽治疗老年急性心肌梗死泵衰竭84例

Observation on Effect of Recombinant Human Brain Natriuretic Peptide in Treatment of Elderly Patients with Acute Myocardial Infarction Pump Failure

赵军峰 1孟淑萍 1柳君 1李国君 1马晓鹏1

作者信息

  • 1. 冀中能源峰峰集团总医院心内科,河北 邯郸 056201
  • 折叠

摘要

Abstract

Objective To observe the clinical effect of recombinant human brain natriuretic peptide ( rhBNP ) for treating the elderly pa-tients with acute myocardial infarction pump failure. Methods 168 cases of elderly acute myocardial infarction pump failure treated in our hospital from October 2011 to December 2014 were selected as the research subjects and randomly divided into the control group and the observation group, 84 cases in each. The control group was treated by the conventional treatment, while on this basis the ob-servation group adopted rhBNP. Results The levels of brain natriuretic peptide ( BNP ) , norepinephrine ( NE ) and creatinine ( SCr ) after treatment in the control group were ( 557 ± 70 ) mg/L, ( 342 ± 28 ) mmol/L and ( 442 ± 128 ) mg/L respectively,which in the observation group were ( 379 ± 51 ) mg/L, ( 217 ± 26 ) mg/L and ( 142 ± 109 )μmol/L, the differences were statistically significant ( P<0. 05 ) . The total effective rate of the observation group was 97. 62%, which was significantly higher than 79. 76% in the control group ( P<0. 05 ) . Conclusion Adopting rhBNP in treating elderly acute myocardial infarction pump failure has significant effect, can obviously reduce the levels of various detection indicators, thus effectively enhance the clinical curative effect, plays the role for inhibiting the left ventricular remodeling, can obviously improve the prognosis, and is worthy of further clinical promotion.

关键词

重组人脑利钠肽/老年急性心肌梗死泵衰竭/疗效

Key words

recombinant human brain natriuretic peptide ( rhBNP )/elderly acute myocardial infarction pump failure/therapeutic effect

分类

医药卫生

引用本文复制引用

赵军峰,孟淑萍,柳君,李国君,马晓鹏..重组人脑利钠肽治疗老年急性心肌梗死泵衰竭84例[J].中国药业,2015,(3):64-64,65,2.

中国药业

1006-4931

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