摘要
Abstract
Objective To observe and compare the effects of Pancreatic Kallidinogenase Enteric-Coated Tablets combined with benazepril in treating diabetic nephropathy. Methods 140 patients with diabetic nephropathy were selected and randomly divided into the combined medication group and the combined medication group, 70 cases in each group. The ACEI group used benazepri alone, while the combined medication group used Pancreatic Kallidinogenase Enteric-Coated Tablets combined with benazepril. The indexes of urinary albumin excretion rate ( UAER ) , blood urea nitrogen ( BUN ) and blood creatinine ( SCR ) before and after treatment were ob-served in the two groups. Results The 24 h urinary protein quantity after treatment in the two group was decreased by 0. 5 g/24 h and more and UAER was decreased by 38. 77 μg/min and more, which were significantly improved compared with before treatment ( P<0. 05 ) , but the combined medication group was significantly superior to the ACEI group ( P<0. 05 ) . Conclusion Pancreatic Kallidino-genase Enteric-Coated Tablets combined with benazepril is better than single benazepri for treating diabetic nephropathy. Pancreatic Kallidinogenase Tablets can improve the renal function, has the clinical application value and deserves to be further researched and pro-moted.关键词
糖尿病肾病/贝那普利/胰激肽原酶肠溶片Key words
diabetic nephropathy/benazepril/Pancreatic Kininogenase Enteric-Coated Tablets分类
医药卫生
