中国药业Issue(8)：60-61,62,3.
抗甲状腺药物治疗孕妇甲状腺功能亢进的疗效及对胎儿的影响
Efficacy of Anti-Thyroid Drugs in Treating Pregnant Women with Hyperthyroidism and Their Influence on Fetus
邹璐 1姚涛 1陈志芳1
作者信息
- 1. 广东省深圳市福田区妇幼保健院妇产科，广东 深圳 518000
- 折叠
摘要
Abstract
Objective To investigate the efficacy of anti-thyroid drugs in treating pregnant women with hyperthyroidism and their influ-ence on fetus. Methods Totally 70 pregnant women with hyperthyroidism were divided into the study group and the control group ac-cording to whether or not accepting the antithyroid drug therapy,35 cases in each group. The pregnant women in the study group were given the anti-thyroid drugs,while the pregnant women in the control group were not given the anti-thyroid drugs. The efficacy and the influence on the fetal development were observed and compared between the two groups. Results The study group had 30 cases of full-term normal delivery,5 cases of premature labor;while the control group had 15 cases of miscarriage or stillbirth,and 15 cases of full-term normal delivery and 5 cases of preterm labor. The neonates in the two groups had no statistically significance differences in the aspects of gender,gestational age,birth weight and so on( P > 0. 05). The total effective rate in the study group was 77. 14%, which was significantly higher than 28. 57% in the control group( P < 0. 05). The FT3,FT4 and TT4 levels had no statistically signifi-cant difference between the study group and the control group( P > 0. 05). Conclusion Anti-thyroid drugs can significantly promote the health of pregnant women with hyperthyroidism and has no obvious adverse reactions on fetus.关键词
抗甲状腺药物/孕妇/甲状腺功能亢进/胎儿Key words
anti-thyroid drugs/pregnant women/hyperthyroidism/curative effect/fetus分类
医药卫生引用本文复制引用
邹璐,姚涛,陈志芳..抗甲状腺药物治疗孕妇甲状腺功能亢进的疗效及对胎儿的影响[J].中国药业,2015,(8):60-61,62,3.
