中国药业Issue(10)：47-48,49,3.
芪苈强心胶囊对慢性充血性心力衰竭患者的疗效及脂联素水平的影响
Effects of Qiliqiangxin Capsule for Treating Chronic Congestive Heart Failure and Its Influence on Plasma Adiponectin Level
王平 1韩兰唐 1张立民1
作者信息
- 1. 北京市大兴区礼贤镇中心卫生院，北京 102604
- 折叠
摘要
Abstract
Objective To investigate the clinical efficacy of Qiliqiangxin Capsule in treating chronic congestive heart failure(CHF) and to evaluate its influence on plasma adiponectin level. Methods Totally 106 patients with chronic CHF were randomly divided into the control group and the observation group,53 cases in each group. The control group used the routine therapy of strong heart,diuresis,ex-panding tube,etc. ,while on this basis the observation group was added with Qiliqiangxin Capsule. The clinical efficacy,left ventricular ejection fraction(LVEF),plasma adiponectin and brain natriuretic peptide(BNP) levels were observed in the two groups. In addition,the related adverse drug reactions during the treatment process were observed in the two groups. Results The total effective rate in the ob-servation group was 83. 02%,which was significantly higher than 73. 58% in the control group( P ﹤ 0. 05);LVEF after treatment was significantly increased compared with before treatment,moreover the improvement in the observation group was more obvious( P ﹤ 0. 05);the plasma adiponectin and BNP levels after treatment in the two groups were significantly decreased compared with before treatment, moreover the improvement in the observation group was more obvious( P ﹤ 0. 05);the occurrence rate of adverse reactions had no sta-tistical difference between the two groups ( P ﹥ 0. 05 ) . Conclusion Qiliqiangxin Capsule has definite effect for treating chronic CHF with good safety,at the same time can significantly decrease the plasma adiponectin level and deserves to be promoted in clinic.关键词
芪苈强心胶囊/慢性充血性心力衰竭/心功能/脂联素Key words
Qiliqiangxin Capsule/chronic congestive heart failure/heart function/adiponectin分类
医药卫生引用本文复制引用
王平,韩兰唐,张立民..芪苈强心胶囊对慢性充血性心力衰竭患者的疗效及脂联素水平的影响[J].中国药业,2015,(10):47-48,49,3.
