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八正汤联合盐酸坦索罗辛缓释胶囊治疗慢性非细菌性前列腺炎48例

李虎宜 杨碧云 刘卫华 刘毅

中国药业Issue(10):103-104,105,3.
中国药业Issue(10):103-104,105,3.

八正汤联合盐酸坦索罗辛缓释胶囊治疗慢性非细菌性前列腺炎48例

Bazheng Decoction Combined with Tamsulosin Hydrochloride Sustained-Release Capsules in Treating 48 Cases of Chronic Non-Bacterial Prostatitis

李虎宜 1杨碧云 1刘卫华 1刘毅1

作者信息

  • 1. 湖北医药学院附属东风医院,湖北 十堰 442008
  • 折叠

摘要

Abstract

Objective To observe the clinical effect of Bazheng Decoction combined with Tamsulosin Hydrochloride Sustained-Release Capsule in treating chronic non-bacterial prostatitis. Methods Totally 96 patients with chronic non-bacterial prostatitis in the hospital from August 2012 to August 2013 were selected and randomly divided into the control group and the treatment group,48 cases in each group. The control group was given Tamsulosin Hydrochloride Sustained-Release Capsule,while on this basis the treatment group was added with Bazheng Decoction. The scores of the US National Institutes of Health-Chronic Prostatitis Symptoms Index(NIH-CPSI)af-ter 2 courses of treatment were compared between the two groups. The curative effects were evaluated. The interleukin-8(IL-8) and tumor necrosis factor-α(TNF-α) levels in expressed prostatic secretion(EPS) were detected. Results The total effective rate after treatment in the treatment group was 91. 67%,which was significantly higher than 79. 17% in the control group,with the difference statistically significant( P ﹤ 0. 05);the NIH-CPSI scores after treatment in the two groups were significantly decreased compared with before treatment ,moreover ,the descend amplitude in the treatment group was significantly more than that in the control group ( P ﹤ 0. 05);the IL-8 and TNF-α levels after treatment in the two groups were significantly decreased compared with before treat-ment ,moreover ,the descend amplitude in the treatment group was significantly more than that in the control group( P ﹤ 0. 05 ). Conclusion Bazheng Decoction combined with Tamsulosin Hydrochloride Sustained-Release Capsule has obviously clinical effect in the treatment of chronic non-bacterial prostatitis,and can improve the clinical symptoms,decrease the inflammatory factors levels and de-serves to be promoted in clinic.

关键词

八正汤/盐酸坦索罗辛缓释胶囊/慢性非细菌性前列腺炎/临床疗效

Key words

Bazheng Decoction/Tamsulosin Hydrochloride Sustained-Release Capsule/chronic non-bacterial prostatitis/clinical effect

引用本文复制引用

李虎宜,杨碧云,刘卫华,刘毅..八正汤联合盐酸坦索罗辛缓释胶囊治疗慢性非细菌性前列腺炎48例[J].中国药业,2015,(10):103-104,105,3.

中国药业

1006-4931

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