摘要
Abstract
Objective To observe the application value of thymosin α1 immunoregulation in senile pulmonary infection. Methods 74 cases of senile pulmonary infection treated in our hospital were divided into the observation group ( 37 cases ) and the control group ( 37 cases ) . The control group was treated by the routine therapy of pulmonary infection, while on this basis the observation group was performed the thymosin α1 immunoregulation therapy. The clinical treatment effects were assessed in the two groups. The immunological indexes and inflammation reaction indexes were detected before and after therapy. Results The total effective rate of the clinical thera-py in the observation group was 91. 89%, which was higher than 78. 38% in the control group, the difference between the two groups was statistically significant ( P < 0. 05 ) . The peripheral blood CD3 +, CD4+, CD4 + /CD8+ levels after treatment in the observation group were increased compared with before treatment ( P < 0. 05 ) , whereas the CD8+ level was decreased than before treatment ( P < 0. 05 );but the peripheral blood CD3 +, CD4+, CD8 +, CD4 + /CD8 + levels in the control group had no statistical differences between before and af-ter treatment ( P > 0. 05 ) . At the same time, the IL-6, IL-8 and TNF-α levels after treatment in the observation group were lower than those in the control group ( P < 0. 05 ) . Conclusion The auxiliary thymosin α1 immunomoregulation therapy in treating senile pul-monary infection can effectively improve the patient ' s immune function;increase the improvement effect of body ' s inflammatory factors, thus promote to increase clinical therapeutic effect.关键词
肺部感染/高龄/胸腺肽α1/免疫调节Key words
lung infection/elderly/thymosin α1 immunoregulation/immunoregulation分类
医药卫生
