中国药业Issue(11)：90-91,92,3.
奥拉西坦联合丁苯酞治疗血管性认知障碍69例
Clinical Observation on Effect of Oxiracetam Combined with Butylphthalide for Treating Vascular Cognitive Impairment in 69 Cases
李春双1
作者信息
- 1. 大庆龙南医院，黑龙江 大庆 163453
- 折叠
摘要
Abstract
Objective To investigate the clinical effect of oxiracetam combined with butylphthalide in the treatment of the patients with vascular cognitive impairment. Methods 138 cases of vascular cognitive impairment were randomly divided into the observation group and the control group according to the random number table, 69 cases in each group. The control group received the oxiracetam treat-ment, while on this basis the observation group was combined with the butylphthalide therapy. The two groups were treated for 4 weeks. The mini-mental state examination ( MMSE ) score, activities of daily life ( ADL ) score and MoCA score before and after treatment were compared between the two groups. Results The MMSE scores after treatment in the observation group were significantly higher than those in the control group, while the ADL scores were significantly lower than those in the control group, the differences were sta-tistically different ( P < 0. 05 );the orientation, delayed recall, attention and visuospatial ability and execution ability scores after treatment in the observation group were significantly higher than those in the control group with statistically significant difference ( P < 0. 05 ) . Conclusion Oxiracetam combined with butylphthalide has significant effect for treating vascular cognitive impairment and important clinical significance.关键词
血管性认知障碍/奥拉西坦/丁苯酞Key words
vascular cognitive impairment/oxiracetam/butylphthalide分类
医药卫生引用本文复制引用
李春双..奥拉西坦联合丁苯酞治疗血管性认知障碍69例[J].中国药业,2015,(11):90-91,92,3.
