摘要
Abstract
Objective To observe the clinical effect of insulin glargine combined with acarbose in treating senile diabetes and to analyze its nursing. Methods 60 elderly patients with type 2 diabetes mellitus ( T2DM ) were selected and divided into the treatment group and the control group randomly and equally. The nursing staff conducted the evaluation on the basic situation of all patients before treatment and performed the health education, dietary nursing, exercise nursing, hypoglycemia prevention, etc. The treatment group was treated by in-sulin glargine combined with acarbose, insulin glargine by subcutaneous injection once daily, oral acarbose tablets 3 times daily;the con-trol group adopted the Insulin Aspart 30 Injection by subcutaneous injection, once before breakfast and again before dinner. The fasting and postprandial blood glucose level, glycated hemoglobin and incidence of hypoglycemia after 16 weeks were observed and compared between the two groups. The blood pressure and blood lipids in the treatment group were compared between before and after treat-ment. Results The postprandial 2 h blood glucose level in the treatment group was significantly higher than that in the control group ( P < 0. 05 ) , the glycated hemoglobin level was higher than that in the control group ( P < 0. 05 ) , the incidence rate of hypoglycemia was lower than that in the control group ( P < 0. 05 );the fasting blood glucose and body mass index had no statistically significant dif-ference between the two groups ( P > 0. 05 );the low density lipoprotein cholesterol after treatment in the treatment group was lower than that before treatment ( P < 0. 05 );the blood pressure, total cholesterol, triacylglycerol and high density lipoprotein cholesterol had no sta-tistical differences compared with those before treatment ( P > 0. 05 ) . Conclusion Insulin glargine combined with acarbose could better control the blood sugar level in elderly patients with T2DM, and has low incidence rate of hypoglycemia and good compliance, which is worth popularization in clinic.关键词
甘精胰岛素/阿卡波糖/老年/2型糖尿病Key words
insulin glargine/acarbose/old man/senile type 2 diabetes mellitus分类
医药卫生
