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参芎葡萄糖注射液中总酚酸含量测定方法研究

朱迪 谭丹 侯靖宇 王爱民 兰燕宇 郑林

中国药业Issue(13):28-29,2.
中国药业Issue(13):28-29,2.

参芎葡萄糖注射液中总酚酸含量测定方法研究

Study on Measurement Method of Total Phenolic Acid Content in Shenxiong Glucose Injection

朱迪 1谭丹 2侯靖宇 1王爱民 1兰燕宇 3郑林1

作者信息

  • 1. 贵阳医学院民族药与中药开发应用教育部工程研究中心,贵州 贵阳 550004
  • 2. 贵阳医学院药学院贵州省药物制剂重点实验室,贵州 贵阳 550004
  • 3. 贵阳医学院药学院,贵州 贵阳 550004
  • 折叠

摘要

Abstract

Objective To establish a method for the determination of total phenolic acid in Shenxiong Glucose Injection. Methods The UV spectrophotometry was adopted with protocatechuic aldehyde as the reference substance, the total phenolic content in Shenxiong Glu-cose Injection was measured. Results The mass concentration of total phenolic acids in the range of 0. 008-0. 030 g/L demonstrated the good linear relation with the absorbance, A=31. 541 04 C-0. 103 97, r=0. 999 6 ( n=5 ) , the average recovery rate was 103. 61% , RSD=4. 85% ( n=9 ) . Conclusion The method is simple, accurate and reliable, and can be used as the quality control method of Shenxiong Glucose Injection.

关键词

参芎葡萄糖/总酚酸/含量测定/紫外分光光度法

Key words

Shenxiong Glucose Injection/total phenolic acid/content determination/ultraviolet spectrophotometry

分类

医药卫生

引用本文复制引用

朱迪,谭丹,侯靖宇,王爱民,兰燕宇,郑林..参芎葡萄糖注射液中总酚酸含量测定方法研究[J].中国药业,2015,(13):28-29,2.

基金项目

国家科技支撑计划课题,项目编号2013BAI11B01;贵州省科技重大专项,项目编号黔科合重大专项字[2011]6019号;贵州省中药现代化专项,项目编号黔科合中药字[2013]5062号。 ()

中国药业

1006-4931

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