中国药业Issue(14)：48-49,50,3.
高血压患者早期强化降压治疗对脑出血的影响
Influence of Early Intensive Antihypertensive Treatment on Intracerebral Hemorrhage in Patients with Hypertension
熊联强 1李颖 1钟华1
作者信息
- 1. 重庆市南川区人民医院神经内科，重庆 408400
- 折叠
摘要
Abstract
Objective To analyze the influence of early intensive antihyertensive treatment on intracerebral hemorrhage(ICH) in patients with hypertension. Methods 58 patients with hypertensive ICH in the hospital from June 2012 to July 2014 were selected and divided into the control group and the ezperimental group according to the computer digital method,29 cases in each group. The control group adopted the routine treatment,while the ezperimental group was given early intensive antihypertensive treatment. The skull CT detection, United States National Institutes of Health Stroke Scale (NIHSS) scores and modified Rankin scale (mRS) scores were adopted to compare the hematoma volume,edema volume and cases of hematoma ezpansion before and after treatment between the two groups,at the same time the clinical curative effect and Barthel indez(BI)were compared between the two groups. Results The NIHSS score at 14 d after treatment in the ezperimental group was obviously lower than that in the control group( P < 0. 05);the hematoma volume and proportion of ezpansion cases of hematoma at 24 h after treatment in the ezperimental group was ( 11. 98 ± 6. 80 ) mL 6. 90%,which was significantly less than ( 14. 75 ± 7. 74 ) mL and 37. 93% in the control group( P < 0. 05);the mRS score identified as moderate and severe disability after 3-month treatment in the ezperimental group accounted for 27. 59%,which was significantly lower than 58. 62%in the control group( P < 0. 05);the total effective rate in the ezperimental group was 96. 55%,which was significantly higher than 65. 52% in the control group( P < 0. 05);the BI score in the ezperimental group was significantly lower than that in the control group ( P < 0. 05);the GCS score before treatment had no statistical difference between the two groups( P > 0. 05),but which at 1 week af-ter treatment in the ezperimental group was significantly higher than that in the control group with statistically significant difference ( P < 0. 05). Conclusion Early intensive antihypertensive treatment can significantly reduce the hematoma ezpansion,reduce the inci-dence rate of cerebral edema,restore and improve the nerve function,and deserves to be clinically promoted.关键词
高血压/脑出血/早期强化降压Key words
hypertension/intra cerebral hemorrhage/early intensive antihy perintension分类
医药卫生引用本文复制引用
熊联强,李颖,钟华..高血压患者早期强化降压治疗对脑出血的影响[J].中国药业,2015,(14):48-49,50,3.
