摘要
Abstract
China is a country of high incidence of esophageal cancer, incidence accounted for more than half of the world, the esophageal cancer mortality rate was 17.38/10 million, ranking the fourth malignant tumor. miRNA is a highly evolutionary conservation of the single stranded RNA newly found, cause the target mRNA degradation or translational inhibition at the post transcriptional level. Abnormal expression of miRNA and esophageal cancer occurrence, differentiation, metastasis and recurrence are closely related. In the peripheral blood, miRNA also showed significant tumor correlation, tumor tissue specificity and tumor expression stability. With the increasing incidence of esophageal cancer, the molecular mechanism of esophageal cancer and early molecular biomarkers will research more deeply. This paper reviewed the study on expression of miRNA occurred in diagnosis and treatment and prognosis of esophageal cancer.关键词
miRNA/食管癌/生物标志物Key words
miRNA/Esophageal cancer/Biomarker分类
医药卫生
