中国医药科学Issue(9)：22-24,62,4.
神经梅毒患者血清白细胞介素-4、干扰素-γ的变化及其临床意义
Changes of serum interleukin-4 and IFN-γ in patients with neurosyphilis and their clinical significance
摘要
Abstract
Objective To investigate the changes of serum interleukin-4(IL-4) and interferon-γ(IFN-γ) in the patients with neurosyphilis and their clinical significance. Methods Thirty-four patients with neurosyphilis(neurosyphilis group) and 34 patients with non-neurosyphilis(non-neurosyphilis group) treated in our hospital from January 2007 to October 2013 were selected, and 34 normal health examinees were selected as the control group. The patients’ blood was drawn to examine the IL-4 and IFN-γafter admission, 1 month after treatment and when not discovering abnormal diseases at the end of health examination. Results The three groups were significantly different in the IL-4 and IFN-γ concentrations(P < 0.05); The neurosyphilis group and the non-neurosyphilis group had higher IL-4 and IFN-γ concentrations than the control group(P < 0.05); The neurosyphilis group and the non-neurosyphilis group were not different in the IL-4 and IFN-γ concentrations, with no statistical significance(P > 0.05); The IL-4 and IFN-γconcentrations of the neurosyphilis group after treatment were significantly lower than those before treatment(P<0.05). Conclusion Both the neurosyphilis group and the non-neurosyphilis group have elevated IL-4 and IFN-γconcentrations;The neurosyphilis group and the non-neurosyphilis group were not significantly different in the IL-4 and IFN-γ;The IL-4 and IFN-γlevels decrease significantly after treatment.关键词
神经梅毒/白细胞介素-4/干扰素-γKey words
Neurosyphilis/Interleukin-4/Interferon-γ分类
医药卫生引用本文复制引用
吕远,周静..神经梅毒患者血清白细胞介素-4、干扰素-γ的变化及其临床意义[J].中国医药科学,2014,(9):22-24,62,4.基金项目
广东省汕尾市医药科技计划项目（2013C016）。 （）
