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C-反应蛋白与糖尿病肾脏微血管病变的相关性分析

郭梁洁 杨林林 杨博

中国医药科学Issue(10):181-183,3.
中国医药科学Issue(10):181-183,3.

C-反应蛋白与糖尿病肾脏微血管病变的相关性分析

The association between C-reactive protein and renal microvascular disease in diabetic

郭梁洁 1杨林林 1杨博1

作者信息

  • 1. 甘肃省窑街煤电集团公司总医院内分泌科,甘肃兰州 730084
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摘要

Abstract

Objective To explore the association between C-reactive protein(CPR) and renal microvascular disease in diabetic.Methods 92 patients with diabetic nephropathy were divided into normal albuminuria group(n=34), microalbuminuria group(n=32), macroalbuminuria group(n=24) according the Mogensen standards. 30 normal cases were selected as control group. The level of serum CPR were detected.Results The level of serum CPR in massive proteinuria group were higher than that in other three groups. The differences were statistically significant(P<0.01). The level of serum CPR in microalbuminuria group were significantly higher than that in normal albuminuria group and the control group. The differences were statistically significant(P<0.01). There were positive correlation between the level of serum CPR and urinary albumin excretion Rate(UAE)(r=0.768,P<0.01).ConclusionThe level of serum CPR is closely related with microvascular lesions of diabetic nephropathy, which is a markers ideal of early diabetic renal damage.

关键词

糖尿病肾病/C-反应蛋白/尿白蛋白的排泄率

Key words

Diabetic nephropathy/C-reaction protein/Urinary albumin excretion rate

分类

医药卫生

引用本文复制引用

郭梁洁,杨林林,杨博..C-反应蛋白与糖尿病肾脏微血管病变的相关性分析[J].中国医药科学,2014,(10):181-183,3.

中国医药科学

2095-0616

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