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13例无功能性阑尾神经内分泌肿瘤临床病理回顾性分析

陈庆明 李明 张洁民 刘丽娜

中国医药科学Issue(13):120-123,4.
中国医药科学Issue(13):120-123,4.

13例无功能性阑尾神经内分泌肿瘤临床病理回顾性分析

Clinical pathology retrospective analysis of 13 patients with nonfunctioning neuroendocrine tumors appendix

陈庆明 1李明 1张洁民 1刘丽娜1

作者信息

  • 1. 甘肃省武威市人民医院病理科,甘肃武威733000
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摘要

Abstract

Objective To investigate the clinical and pathological characteristics of immune phenotype and prognosis of the non-functional appendix neuroendocrine tumor.Methods The clinical pathological data of 13 cases with no functional neuroendocrine tumor of the appendix were retrospectively analyzed, then the changes of tumor was observed, and immunohistochemistry were done. Results No functional appendix neuroendocrine tumors could be divided into four clinical pathologic stage, which pathological features, biological behavior and prognosis were different. Incidence of non-functional appendix neuroendocrine tumor G1 were 8 cases, G2 were 3 cases, G3 or neuroendocrine carcinoma were 2 cases, immunohistochemical examination showed that, AE1 / AE3 positive were 3 cases, the Syn positive were 11 cases, CgA positive were 10 cases. 5 survival rates in three level during follow-up period were 100%, 100%, 51% respectively.ConclusionNon-functional appendix neuroendocrine tumor pathological grading and clinical staging is closely related to the prognosis, and has guidance for treatment, reasonable application of immunohistochemical can improve the diagnosis rate of neuroendocrine tumor, reduce the clinical misdiagnosis, and avoid excessive treatment.

关键词

阑尾肿瘤/神经内分泌肿瘤/临床病理分析

Key words

Appendix tumor/Neuroendocrine tumor/Clinical pathological analysis

分类

医药卫生

引用本文复制引用

陈庆明,李明,张洁民,刘丽娜..13例无功能性阑尾神经内分泌肿瘤临床病理回顾性分析[J].中国医药科学,2014,(13):120-123,4.

中国医药科学

2095-0616

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