中国医药科学Issue(13)：186-187,198,3.
恶性肿瘤GP方案化疗中外周血网织血小板变化的临床研究
Clinical research on the change of reticulated platelet in cancer patients receiving GP
摘要
Abstract
Objective To explore the predictive role of reticulated platelet on bone marrow recovery in cancer patients receiving gemcitabine-based regimen.MethodsFrom January 2009 to December 2013, a total of 38 cancer patients receiving gemcitabine-based chemotherapy were collected at zhongshan city people's hospital. reticulated platelet and platelet count from pre-chemotherapy to every 3 days post-chemotherapy were tested.Results For a total of 36 patients, compared to chemotherapy-induced thrombocytopenia (CIT) without imminent recovery, CIT with imminent recovery had statistically significant higher reticulated platelet count[(8.40±3.95)×109/L vs (5.77±3.58)×109/L,t=3.04,P= 0.003] and was not statistically significant higher platelet count[(51.34±11.20) ×109/L vs (46.71±10.58) ×109/L,t=1.85,P=0.068].ConclusionFor cancer patients receiving gemcitabine combined with cisplatin, peripheral blood reticulated platelets may be more effective than platelet in predicting bone marrow megakaryocytes recovery.关键词
吉西他滨/网织血小板/恶性肿瘤/化疗Key words
Gemcitabine/Reticulated platelet/Cancer/Chemotherapy分类
医药卫生引用本文复制引用
萧剑军,何洁冰,彭杰文,殷兆锋,江小梅..恶性肿瘤GP方案化疗中外周血网织血小板变化的临床研究[J].中国医药科学,2014,(13):186-187,198,3.基金项目
2011年中山市卫生局科研立项课题，项目编号2011A050132 （）
