摘要
Abstract
Objective To compare the clinical efficacy of lamivudine alone and lamivudine in combination with salvia tablet for treatment of chronic hepatitis B. Methods 78 patients with chronic hepatitis B in our hospital were selected and assigned to two groups.The two groups were given lamivudine alone or lamivudine in combination with salvia respectively.The therapeutic indictors were compared between the two groups. Results The experimental group had significantly higher negative conversion rate than the control group, with statistical significance(P < 0.05). When comparing serum hepatic fibrosis between the two groups,the experimental group had significantly better hepatic fibrosis indicator than the control group,with statistical significance(P < 0.05).In the control group,1 case had fatigue and nausea which regressed after symptomatic treatment;1 case had mild elevation of blood pressure which was back to normal after symptomatic treatment. The experimental group had no adverse reaction. Conclusion Lamivudine in combination with salvia tablet has good efficacy for treatment of chronic hepatitis B with significant improvement or delay of hepatic fibrosis,thus it is worthy of clinical promotion for treatment of chronic hepatitis B.关键词
拉米夫定/丹参片/慢性乙型肝炎/疗效观察Key words
Lamivudine/Salvia tablet/Chronic hepatitis B/Efficacy observation分类
医药卫生
