中国医药科学Issue(15)：158-160,3.
妊娠期肝内胆汁淤积症胆汁酸、肝酶指标对妊娠结局的影响
Influence of bile acids and liver enzyme indicators of gestational patients with intrahepatic cholestasis on pregnancy outcomes
黄满辉 1张翠1
作者信息
- 1. 广东省东莞市清溪医院妇产科，广东东莞523660
- 折叠
摘要
Abstract
Objective To analyze the influence of the bile acids and liver enzyme indicators of gestational patients with intrahepatic cholestasis on the pregnancy outcomes and provide reference for the clinical diagnosis and treatment of gestational patients with intrahepatic cholestasis. Methods 170 gestational patients with intrahepatic cholestasis treated in our hospital from January 2012 to October 2013 were selected as the clinical study subjects and all the patients were given bile acids and liver enzyme indicators detection. The patients were divided into the mild, moderate and severe groups according to the detection results and 150 normal healthy pregnant women admitted to our hospital in the same period were selected as the control group. The pregnancy outcomes of the four groups of pregnant women were observed. Results Regarding to postpartum bleeding, the gestational patients with severe intrahepatic cholestasis had the highest incidence, with statistically significant difference(P < 0.05). The gestational patients with severe intrahepatic cholestasis had higher proportion of cesarean section, higher neonatal asphyxia rate, higher proportion of low birth weight infants and lower neonatal Apgar score, with statistically significant differences to the other groups. Conclusion The detection of bile acids and liver enzyme indicators of the gestational patients with intrahepatic cholestasis is conducive to determining the severity of illness and thus evaluating maternal and neonatal outcomes.关键词
妊娠期肝内胆汁淤积症/胆汁酸/肝酶指标/妊娠结局Key words
Gestational intrahepatic cholestasis/Bile acids/Liver enzymes indicators/Pregnancy outcomes分类
医药卫生引用本文复制引用
黄满辉,张翠..妊娠期肝内胆汁淤积症胆汁酸、肝酶指标对妊娠结局的影响[J].中国医药科学,2014,(15):158-160,3.
