摘要
Abstract
ObjectiveTo investigate the clinical intervention effects of levofloxacin on acute pyelonephritis. Methods110 patients with acute pyelonephritis who were treated in our hospital from April 2010 to November 2013 were randomly divided into the clinical group and the reference group, with 55 patients in each group. The clinical group received intravenous drip of levofloxacin and then oral administration; The reference group received intravenous drip of penbritin and then oral administration of sulfamethoxazole. The symptom and sign disappearance time, clinical efficacy and treatment time of the two groups were compared.ResultsAfter the end of medication, the symptoms and sings improved gradually. The clinical group was significantly better than the reference group in both symptom and sign disappearance time, with statistically significant differences (P<0.05). The total effective rate of the clinical group was 98.18% and that of the reference group was 96.36%, with no statistically significant difference between the two groups (P>0.05). But the clinical group had significantly shorter average treatment duration than the reference group (P<0.05), with statistically significant difference. In the clinical group, 1 patient had nausea and vomiting, 1 patient had dizziness, and 1 patient had skin itch; In the reference group, 4 patients had nausea and vomiting. The two groups were not significantly different in the incidence of adverse reactions (P>0.05). ConclusionIn the treatment of acute pyelonephritis, the application of levofloxacin shows accurate efficacy, relieves symptoms and signs rapidly, and has short treatment course and good safety.关键词
急性肾盂肾炎/左氧氟沙星/氟喹诺酮Key words
Acute pyelonephritis/Levofloxacin/Fluoroquinolone分类
医药卫生
