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复方四季青软膏的制备及质量控制

涂金兰 蔡绚 尹航 杨信定 何雨 石白冰

中国医药科学Issue(18):29-33,5.
中国医药科学Issue(18):29-33,5.

复方四季青软膏的制备及质量控制

Preparation and quality control of compoundointment for Sijiqing

涂金兰 1蔡绚 1尹航 1杨信定 1何雨 2石白冰2

作者信息

  • 1. 贵阳医学院附属医院药剂科,贵州贵阳550004
  • 2. 贵阳医学院药学系,贵州贵阳550004
  • 折叠

摘要

Abstract

Objective To identify the authenticity of the main drug in compound Sijiqing ointment; to study the preparation method of compound Sijiqing ointment; to establish a method to control the content of compound Sijiqing ointment. Methods Using the TLC method to identify the four leaf, rhubarb, Radix Arnebia; Determination of the content of levo shikonin in shikonin by UV spectrophotometry. Results The ethanol solution of levo shikonin was in the range of 5.64-33.87μg/mL,showed a good linear relationship between A and C,r=0.9999 (n=6),the average recovery was 98.80%,RSD (%)=0.88 (n=6). Conclusion The method is accurate, simple, good reproducible line,It can be used to control the content of shikonin in compound ointmentin Sijiqing.

关键词

复方四季青软膏/含量测定/左旋紫草素

Key words

Compound Sijiqing ointment/Determination of content/Levo shikonin

分类

医药卫生

引用本文复制引用

涂金兰,蔡绚,尹航,杨信定,何雨,石白冰..复方四季青软膏的制备及质量控制[J].中国医药科学,2014,(18):29-33,5.

基金项目

贵州省科技厅中药现代化科技产业研究开发专项项目(黔科合中药字[2011]5011号)。 ()

中国医药科学

2095-0616

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