摘要
Abstract
Objective To explore the effect of noninvasive positive pressure ventilation on chronic obstructive pulmonary disease complicated with respiratory failure. Methods A total of 112 chronic obstructive pulmonary disease patients with complication of respiratory failure admitted from 2010 to 2013 were selected, and randomly divided into control group and experimental group by half in which the control group using conventional treatment, while the experimental group using noninvasive positive pressure ventilation treatment. Then comparing hospitalization, intubation rate, mortality and indicators of blood gas analysis before and after treatment (for example partial pressure of oxygen, carbon dioxide partial pressure, pH). Results Hospitalization, intubation and mortality rates were compared between two groups, the indicators for control group were significantly higher than the experimental group, the difference was statistically significant (P<0.05). Partial pressure of oxygen, partial pressure of carbon dioxide and pH were compared between two groups, the difference was without statistically significant (P>0.05) before treatment, but the partial pressure of oxygen in the control group was lower than the experimental group after treatment, however the carbon dioxide partial pressure in the control group was higher than the experimental group after treatment, the difference was statistically significant (P < 0.05).Intubation in the control group was 15.00%, while the experimental group was 3.57% intubation, the difference was statistically significant (P < 0.05). Conclusion Noninvasive positive pressure ventilation is invasive, safe and effect on COPD complicated with respiratory failure. It deserves extensive clinical application.关键词
无创正压通气/慢性阻塞性肺疾病/呼吸衰竭Key words
Noninvasive positive pressure ventilation/Chronic obstructive pulmonary disease/Respiratory failure分类
医药卫生
