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35例肾移植患者他克莫司血药浓度监测分析

马爱玲 赵宁民 赵红卫 秦玉花 张海峰 王漪檬

中国医药科学Issue(23):50-51,68,3.
中国医药科学Issue(23):50-51,68,3.

35例肾移植患者他克莫司血药浓度监测分析

Analysis of blood concentration data of tacrolimus in 35 renal transplantation patients

马爱玲 1赵宁民 1赵红卫 1秦玉花 1张海峰 1王漪檬1

作者信息

  • 1. 河南省人民医院药学部,河南郑州450003
  • 折叠

摘要

Abstract

Objective To investigate the relationship between tacrolimus blood drug concentration of renal transplantation patients in different periods and dose. Methods Drug concentration of blood of 35 cases of renal transplantation patients was monitored for a long time. The relationship of postoperative time, dosage and tacrolimus blood concentrations was analyzed. Results 35 cases of renal transplantation patients a total of 195 times blood drug concentration was monitored with individual blood drug concentration. Blood drug concentration is higher 1 month after renal transplantation surgery while the tacrolimus concentration with 4 ~ 8ng/mL is suitable after more than a month. Conclusion Considering the tacrolimus narrow therapeutic window, we suggest monitoring blood drug concentration.

关键词

肾移植/他克莫司/血药浓度

Key words

Renal transplantation/Tacrolimus/Blood drug concentration

分类

医药卫生

引用本文复制引用

马爱玲,赵宁民,赵红卫,秦玉花,张海峰,王漪檬..35例肾移植患者他克莫司血药浓度监测分析[J].中国医药科学,2014,(23):50-51,68,3.

基金项目

河南省常州四药临床药学科研基金资助项目(CZSYJJ13030)。 ()

中国医药科学

2095-0616

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