中国医药科学Issue(3):66-69,4.
基层医院肺炎克雷伯菌的临床感染分布和耐药谱分析
Analysis of drug resistant spectrum and distribution of clinical infection of Klebsiella pneumonia in primary hospital
李忠 1曾金红 1李亚 1李霞 1甘海鹰 1温丽娴 1林城 1彭友海1
作者信息
- 1. 广东省东莞市石排医院,广东东莞523330
- 折叠
摘要
Abstract
Objective Through the statistics of the analysis of drug resistant spectrum and the distribution of clinical infection of Klebsiella pneumonia in primary hospital, to provide clinical basis for the application of the antibiotic drugs. Methods 298 strains of Klebsiella pneumoniae which were separated from inpatients in primary hospital from June 2012 to November 2013 were selected to analyze thedrug resistant spectrum through the distribution of clinical infection, and the screening and confirmation of ESBLs-producing strains. Results The specimen of strains source of Klebsiella pneumonia in primary hospital from sputum, urine and throat swab were 76.51%, 11.07%and 5.03%, while the infected patients had got ill in respiratory system(43.96%), digestive system(25.50%) and hematological system (19.46%). The resistant rates of ESBLs-producing strains of Klebsiella pneumonia were higher than those of non-ESBLs-producing strains, the treatment effect of mixture combined enzyme inhibitor in bacteria of enzyme production were better than antibiotics alone, there were significant difference(P < 0.05). Conclusion ESBLs-producing strains of Klebsiella pneumonia in primary hospital which has serious drug resistance, should be applied reasonably of antibiotics to delay the drug resistance and to control the nosocomial infection, according to the drug sensitivity results.关键词
基层医院/肺炎克雷伯菌/分布/耐药谱Key words
Primary hospital/Klebsiella pneumonia/Distribution/Drug resistant spectrum分类
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李忠,曾金红,李亚,李霞,甘海鹰,温丽娴,林城,彭友海..基层医院肺炎克雷伯菌的临床感染分布和耐药谱分析[J].中国医药科学,2015,(3):66-69,4.