摘要
Abstract
ObjectiveTo investigate effect of tiotropium bromide and large dose of salmeterol xinafoate fluticasone propionate in patients with bronchial asthma combined with COPD.Methods71 patients of bronchial asthma combined with COPD were randomly divided into observation group(n=36 cases)and control group(n=35 cases). The two groups were given conventional treatment.The control group was given tiotropium bromide and moderate dose of salmeterol xinafoate fluticasone propionate,while the observation group was given tiotropium bromide and large dose of salmeterol xinafoate fluticasone propionate.Efficacy of the two groups was compared.Results ACT score of pre-treatment,and 1 month,6 month,12 month in two groups had no significant difference(P>0.05).After 1 years of treatment,FEV1% estimates,FEV1 increase,Delta PEF,acute exacerbation onset time,interval time,CAT score of observation group were significantly better than that of the control group(P<0.05).Conclusion Tiotropium bromide and large dose of salmeterol xinafoate fluticasone propionate in patients with bronchial asthma combined with COPD can significantly improve lung function,relieve the acute exacerbation of symptoms,improve the quality of life,and is worthy of promotion.关键词
噻托溴铵/沙美特罗氟替卡松/支气管哮喘/COPDKey words
Tiotropium bromide/Salmeterol xinafoate fluticasone propionate/Bronchial asthma/COPD分类
医药卫生
