中国医药科学Issue(6):18-21,25,5.
围生期静脉血栓栓塞症42例临床诊治分析
Clinical analysis of diagnosis and treatment of 42 cases with venous thromboembolism (VTE) in perinatal period
骆曦图 1杨澄宇 2刘正军1
作者信息
- 1. 广州医科大学附属第三医院普外科,广东广州510150
- 2. 南方医科大学,广东广州510515
- 折叠
摘要
Abstract
Objective To study the diagnosis and treatment, the preventive measures and the maternal-neonatal outcomes of VTE in perinatal period. Methods 42 cases with VTE in perinatal period who were treated in the Third Affiliated Hospital of Guangzhou Medical University between January 2009 and January 2014 were analyzed retrospectively. Results (1)37 cases (88.1%) were diagnosed with color Doppler imaging, 5 cases were diagnosed with MRI which suggested that thrombosis positive while color Doppler imaging suggested that thrombosis negative. There were 32 cases (76.2%) with thrombosis in left lower extremity, 9 cases (21.4%) with thrombosis in right lower extremity, 1 case (2.4%) with thrombosis in both lower limbs, 33 cases (78.6%)with central thrombosis, 3 cases (9.5%) with peripheral thrombosis and 5 cases (11.9%) with mixed thrombosis. (2)Treatment:42 cases were treated with anticoagulant therapy of low molecular weight heparin (LMWH), 11 cases were treated with inferior vena cava filters insertion, 6 cases were treated with catheter thrombolysis. There was no lethality pulmonary embolism, and all patients were improved and discharged after the systematic treatment. The situation of vascular recanalization in patients who were treated with catheter thrombolysis was better after 72 hours, 3 months and 6 months compared with which in patients who were treated with anticoagulation alone, there were statistical significance(P < 0.05). Conclusion VTE in perinatal period has high incidence, could induce severe complications, should be treated with appropriate therapy and thrombolysis based on anticoagulation through the specific different pregnancy to prevent and reduce the complication, in order to improve the maternal-neonatal outcomes and to reduce the sequela of deep venous thrombosis.关键词
围生期/深静脉血栓形成/预防/治疗Key words
Perinatal period/Deep venous thrombosis/Prevention/Treatment分类
医药卫生引用本文复制引用
骆曦图,杨澄宇,刘正军..围生期静脉血栓栓塞症42例临床诊治分析[J].中国医药科学,2015,(6):18-21,25,5.