摘要
Abstract
Objective To evaluate and compare the effect of dexmedetomidine and ketamine on subarachnoid block. Methods 120 patients who were undergoing elective subarachnoid space block anesthesia were divided into three groups according to random number table,with 40 cases in each group.Patients in normal saline group (NS group) were intravenously dripped of 10mL normal saline in 10min,with the dripping speed of 5mL/h,patients in dexmedetomidine group (DEX group) were intravenously pumped of dexmedetomidine,with the load quantity of 0.5μg/kg,and then keeping the venous malntenance rate of 0.5μg/(kg·h),patients in ketamine group (KET group) were intravenously dripped of 0.2mg/kg ketamine, and then keeping the venous malntenance rate of 0.5μg/(kg·h) Results The effect onset time of anesthesia in KET group was much quicker than which in NS group(P<0.05).The time of reaching the best anaesthetic effect among the three groups was no statistical significance(P>0.05).The time of sensory restoration and motor function recovery in KET group and in DEX group had obviously longer than which in NS group(P<0.05). Conclusion Dexmedetomidine and ketamine on subarachnoid space block anesthesia have similar synergistic effect,while ketamine is much stabler on patients' hemodynamics.关键词
右美托咪定/氯胺酮/蛛网膜下腔阻滞Key words
Dexmedetomidine/Ketamine/Subarachnoid block分类
医药卫生
