摘要
Abstract
Objective To investigate the curative effect of minimally invasive cholecystolithotomy with gallbladder reservation combined tauroursodeoxycholic acid in the treatment of cholecystolithiasis,and contrast with laparoscopic cholecystectomy. Methods 80 patients with cholecystolithiasis from 2011 April to 2013 April in our hospital were randomly divided into study group and control group with 40 cases in each group,the study group were treated with minimally invasive cholecystolithotomy with gallbladder reservation combined tauroursodeoxycholic acid treatment. The control group was given conventional laparoscopic cholecystectomy treatment.The operation time,intraoperative bleeding volume,postoperative hospitalization time and time to resume diet of patients in two groups and symptoms,gallbladder wall thickness,gallbladder contraction function and recurrence rate of patients in study group before operation and 1 year after operation were observed. Results The intraoperative bleeding volume of the study group was significantly less than the control group,postoperative time to resume diet was significantly shorter(P <0.05). After one year of follow-up,the incidence of symptoms of the study group was significantly lower,gallbladder wall thickness was thinned,gallbladder contraction function improved significantly(P < 0.05);and the recurrence rate of cholecystolithiasis was only 5.0%. Conclusion The effect of minimally invasive cholecystolithotomy with gallbladder reservation combined tauroursodeoxycholic acid in the treatment of cholecystolithiasis is better than laparoscopic cholecystectomy,and it can obviously improve the gallbladder contraction function,reduce the recurrence rate.关键词
微创保胆取石术/牛磺熊去氧胆酸/腹腔镜胆囊切除术/胆囊结石Key words
Minimally invasive cholecystolithotomy with gallbladder reservation/Tauroursodeoxycholic acid/Laparoscopic cholecystectomy/Cholecystolithiasis分类
医药卫生
