中国医院用药评价与分析Issue(7)：657-660,4.
1例慢性肾炎并发尿路感染患者的抗菌药物用药分析与药学监护
Antibiotic Use and Pharmaceutical Care for a Patient with Chronic Nephritis Complicating with Urinary Tract Infection
彭玲娜1
作者信息
- 1. 永州市中心医院 南院 药剂科，湖南永州 425006
- 折叠
摘要
Abstract
OBJECTIVE:To provide references for rational use of antibiotics in patient with chronic nephritis complicating with urinary tract infection. METHODS:The rationality in drug selection,usage,dosage,replacement and reduced-order treatment in the antibiotic use in one patient with chronic nephritis complicating with urinary tract infection was analyzed based on patient’s re-nal function,the common pathogens causing urinary tract infection and drug resistance;meanwhile,the medication regimen was optimized. RESULTS:There is a certain theoretical basis for the empiric regimen of aztreonam for treatment of urinary tract infec-tion,but the drug concentration was too high,which was then replaced by piperacillin/tazobactam;however,pharmacists recom-mended further optimization using cefoperazone/sulbactam instead. The timing of reduced-order treatment was less than rational. CONCLUSIONS:It is advisable to choose antibiotics with mild renal toxicity for patients with renal dysfunction in that the over-dose or high concentration may cause adverse reactions. The empiric use of antibiotics should be based on the type of infection as well as the antibiotic resistance of common pathogens and it is better to choose the broad-spectrum antibiotics. Reduced-order treat-ment should be performed timely and it is better to choose relatively narrow-spectrum antibiotics targeted at specific pathogens based on susceptibility results.关键词
慢性肾炎/尿路感染/抗菌药物/药学监护Key words
Chronic nephritis/Urinary tract infection/Antibiotics/Pharmaceutical care分类
医药卫生引用本文复制引用
彭玲娜..1例慢性肾炎并发尿路感染患者的抗菌药物用药分析与药学监护[J].中国医院用药评价与分析,2014,(7):657-660,4.
