中国医院用药评价与分析Issue(12):1144-1146,3.DOI:10�14009/j.issn.1672-2124.2014.12.030
2013年381例药品不良反应报告分析
Adverse Drug Reaction Reports in 2013:Analysis of 381 Cases
刘静静 1张伟 1康艳生 1王晓琴 1徐小亚 1姬润调 1申雅妮 1张鹤凤1
作者信息
- 1. 陕西榆林市第一医院药剂科,陕西榆林719000
- 折叠
摘要
Abstract
OBJECTIVE: To investigate the characteristics and regularity of the adverse drug reactions ( ADRs) occurred in Shaanxi Yulin First Municipal Hospital ( hereinafter referred to as “our hospital”) so as to reduce the incidence of ADR and promote rational use of drugs. METHODS:A total of 381 ADR case reports collected by clinical pharmacy room of pharmacy department of our hospital in 2013 were statistically analyzed and evaluated using regression analysis. RESULTS:Of the 381 ADR cases, males showed high proportion than females [(52�76%(201 cases) vs. 47�24%( 180 cases ) ]; the patients aged 51⁃70 years took the lead with 240 cases ( 62�99%); the inpatients outnumbered the outpatients [ 348 ( 91�34%) vs. 33 ( 8�66%) ];173 cases ( 45�41%) were induced by anti⁃infective drugs,327 cases(85�83%) by intravenous drip infusion;156 cases(40�94%) manifested as lesions of skin and its appendages. 342(89�76%) were common ADRs;303(79�53%) were cured;171 cases(44�88%) were considered as “most probably” in cause⁃effect relationship. CONCLUSIONS: The occurrence of ADR is closely associated with clinic;it is important for hospital to attach great importance to the ADR monitoring and reporting so as to promote clinical rational use of drugs.关键词
药品不良反应/相关因素/分析Key words
Adverse drug reaction/Related factors/Analysis分类
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刘静静,张伟,康艳生,王晓琴,徐小亚,姬润调,申雅妮,张鹤凤..2013年381例药品不良反应报告分析[J].中国医院用药评价与分析,2014,(12):1144-1146,3.