双环醇片与水飞蓟宾胶囊治疗抗结核药药物性肝损伤的疗效比较OA
Efficacy of Bicyclol Tablets vs.Silymarin Capsules in the Treatment of Anti-tuberculosis Drug-induced Liver Injury
目的：比较双环醇片与水飞蓟宾胶囊在治疗抗结核药药物性肝损伤的疗效差异。方法：将河南省鹤壁市传染病医院2012年6月至2014年8月门诊治疗的抗结核药药物性肝损伤患者按就诊时间顺序逐一分入研究组和对照组，研究组服用双环醇片，对照组服用水飞蓟宾胶囊，于治疗1、2、4周末复查肝功能，比较治疗效果。结果：研究组在治疗1 w后丙氨酸氨基转移酶（ ALT）较对照组改善明显。治疗1周末及2周末研究组疗效优于对照组，而第4周末两组均可达到较高的有效率，疗效相当。…查看全部>>
OBJECTIVE:To evaluate the efficacy of bicyclol tablets vs.silymarin capsules in the treatment of anti-tuberculosis drug-induced liver injury.METHODS: The outpatients with anti-TB drug-induced liver injury seen in Henan Hebi Hospital of Infectious Diseases from June 2012 to August 2014 were assigned to either trial group receiving bicyclol tablets or control group receiving silymarin capsules.The liver function of the patients at 1, 2 and 4 weeks were followe…查看全部>>
张林;王永素
河南省鹤壁市传染病医院结核科，河南鹤壁 458000河南省鹤壁市传染病医院结核科，河南鹤壁 458000
医药卫生
双环醇水飞蓟宾抗结核药药物性肝损伤
BicyclolSilymarinAnti-tuberculosis drugsDrug-induced liver injury
《中国医院用药评价与分析》 2015 (4)
519-520,521,3
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