中国医院用药评价与分析Issue(5)：670-670,671,2.DOI:10.14009/j.issn.1672-2124.2015.05.040
利巴韦林治疗婴幼儿轮状病毒肠炎的疗效与安全性
Efficacy and Safety of Libavirin for Infantile Rotavirus Enteritis
牛辛元1
作者信息
- 1. 天津市河西区桃园街社区卫生服务中心西药房，天津 300204
- 折叠
摘要
Abstract
OBJECTIVE:To evaluate the efficacy and safetyof ribavirin for infantile rotavirus enteritis.METHODS:Between May 2012 and April 2014, a total of 164 children with rotavirus enteritis in our hospital were randomized to either treatment group or control group of 82 cases each.The patients in the treatment group were treated with ribavirin while those in the control group were treated with conventional therapy.RESUTLS:The total response rate in the treatment group was significantly higher than in the control group[91.5%(75/82) vs.73.2%(60/82);P<0.05] and the treatment cost, the incidence of enteritis, the cure time of enteritis and the incidence of adverse drug reactions in the treatment group were also significantly higher than in the control group(P<0.05).CONCLUSIONS:Ribavirin was proved to be a feasible, safe and effective therapy for infantile rotavirus enteritis, thus its use is worth of clinical recommendation.关键词
利巴韦林/婴幼儿/轮状病毒肠炎/临床疗效Key words
Ribavirin/Infants/Rotavirus enteritis/Clinical response分类
医药卫生引用本文复制引用
牛辛元..利巴韦林治疗婴幼儿轮状病毒肠炎的疗效与安全性[J].中国医院用药评价与分析,2015,(5):670-670,671,2.
