中国医院用药评价与分析Issue(7):911-912,2.DOI:10.14009/j.issn.1672-2124.2015.07.025
万古霉素在革兰阳性菌感染新生儿中血药浓度的监测与应用分析
Monitoring of Blood Concentration of Vancomycin and Analysis of Its Use in Neonates
李际红1
作者信息
- 1. 深圳市福田区妇幼保健院药剂科,广东深圳 518045
- 折叠
摘要
Abstract
OBJECTIVE:To monitor the blood concentration of vancomycin and evaluate its clinical application in neonates so as to provide theoretical basis for the clinical use of vancomycin.METHODS:A retrospective analysis was performed on the data of a total of 40 neonates in Shenzhen Futian District Maternal and Child Health Hospital who used vancomycin for management of infection from January 2013 to December 2014 .RESULTS: In the total 40 patients, 10 kinds of pathogens were identified; serum procalcitonin concentration in 36 cases decreased to less than 0.5 ng/ml after treatment by vancomycin, with the total effective rate of vancomycin for sampled neonates at 90.00%(36/40).CONCLUSIONS:Vancomycin is effective for treatment of neonates with gram-positive bacteria infection.关键词
新生儿/革兰阳性菌感染/万古霉素/血药浓度监测/临床用药分析Key words
Neonates/Blood concentration monitoring/Vancomycin/Analysis of clinical drug use分类
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李际红..万古霉素在革兰阳性菌感染新生儿中血药浓度的监测与应用分析[J].中国医院用药评价与分析,2015,(7):911-912,2.