中国医院用药评价与分析Issue(7)：937-938,2.DOI:10.14009/j.issn.1672-2124.2015.07.038
联合应用支气管扩张剂治疗慢性阻塞性肺疾病合并呼吸衰竭的疗效观察
Efficacy of Combined Bronchodilator Therapy for Patients with Chronic Obstructive Pulmonary Disease Complicated by Respiratory Failure
徐永强1
作者信息
- 1. 高州市石鼓镇中心卫生院呼吸内科，广东茂名 525252
- 折叠
摘要
Abstract
OBJECTIVE:To evluate the clinical effiacy of combined bronchodilator therapy in treating patients with chronic obstructive pulmonary disease(COPD)complicated by respiratory failure.METHODS:126 cases of COPD patients with respiratory failure were randomized to two groups of 63 cases each, and were treated with tiotropium bromide plus ambroxol hydrochloride inhalation alone(control group)or in combination with salbutamol inhalation(treatment group)The clinical efficacy of the two groups of patients were followed and evaluated.RESULTS: The total effective rate in the observation group was significantly higher than in the control group[92.06%(58/63)vs.79.37%(50/63)](P<0.05);after treatment, the PaO2 , FEV1 and FEV1%were significantly higher while PaCO2 was significantly lower in the observation group than in the control group(P<0.05).CONCLUSIONS:Combined use of bronchodilators can correct respiratory failure and improve pulmonary function in patients with COPD associated with respiratory failure.关键词
支气管扩张剂/噻托溴铵/沙丁胺醇/联合应用/慢性阻塞性肺疾病/呼吸衰竭Key words
Bronchodilator/Tiotropium bromide/Salbutamol/Combined use/Chronic obstructive pulmonary disease/Respiratory failure分类
医药卫生引用本文复制引用
徐永强..联合应用支气管扩张剂治疗慢性阻塞性肺疾病合并呼吸衰竭的疗效观察[J].中国医院用药评价与分析,2015,(7):937-938,2.
