中国真菌学杂志Issue(1)：22-24,5,4.
国产盐酸特比萘芬对皮肤癣菌的体外抗菌活性研究
In vitro susceptibility testing of domestic terbinafine hydrochloride against dermatophytes
摘要
Abstract
Objectives To investigate the in vitro susceptibility testing of terbinafine against 138 strains of dermatophytes.Meth⁃ods CLSI M38⁃A2 guideline was applied.The media containing the fungi in the concentration of(0.4⁃5)×104 CFU/mL were incuba⁃ted at 30 for 7 days.The MIC endpoint was determined as the first concentration of antifungal agent that reached 100% inhibition of growth compared with the growth control.The MEC endpoint was determined as the first concentration of antifungal agent that reached 50% inhibition of growth compared with the growth control.Results The tested 138 strains of Dermatophytes were susceptible to ter⁃binafine,MEC range:0.008⁃0.125μg/mL,MIC 0.008⁃0.25μg/mL.There was no statistical differences between Beijia terbinafine and imported terbinafine(P>0.05).Conclusion Beija Terbinafine is active aganist Dermatophytes.It can be an effective choice in super⁃ficial mycosis treatment.关键词
国产盐酸特比萘芬/皮肤癣菌/体外/抗菌活性Key words
domestic terbinafine hydrochloride/dermatophytes/in vitro/antifungal susceptibility tests分类
医药卫生引用本文复制引用
谈鑫,沈帅帅,朱双,姚志荣,郑捷,邓丹琪,廖万清,潘炜华,邓淑文,郭芸,雷文知,张超,周兆婧,方文捷,闻轶旸..国产盐酸特比萘芬对皮肤癣菌的体外抗菌活性研究[J].中国真菌学杂志,2015,(1):22-24,5,4.基金项目
国家自然科学基金（31270180），上海医学真菌分子重点实验室基金 （）
