中国执业药师Issue(6)：20-23,4.DOI:10.3969/j.issn.1672-5433.2014.06.005
鹿茸益肾胶囊治疗肾阳虚证阳痿的药效学研究
Pharmacodynamic Study of Lurongyishen Capsules on the Treatment of Impotence with Kidney Yang Deficiency Syndrome
摘要
Abstract
Objective: To study the pharmacodynamic mechanism of lurongyishen capsules in the treatment of impotence with kidney yang deficiency syndrome. Methods: To observe the effects of lurongyishen capsules on penile erection latency in castrated male rats, the effects on the accessory sex organs, pituitary, adrenal, thymus and spleen weight coefficient of castrated male rats, the influence on their serum gonadal hormone content and the impact on hydrogen hydrocortisone induced yang deficiency model mice. Results: Lurongyishen capsules can improve the excitation of the penis to stimulation of castrated male rats and significantly shorten the erectile latency, improve the accessory sex organs, pituitary and adrenal weight coefficient, reduce the thymus and spleen weight coefficient, significantly increase rats’ serum testosterone(T) and cortisol (F) levels, decrease serum luteinizing hormone (LH) and follicle-stimulating hormone (FSH) contents, improve yang deficiency syndrome and enhance the vitality of mice. Conclusion: Lurongyishen capsules have a function of reinforcing kidney, and can be used in the treatment of kidney yang deficiency impotence and sexual dysfunction.关键词
鹿茸益肾胶囊/药效学/肾阳虚证/阳痿/动物模型Key words
Lurongyishen Capsules/Pharmacodynamics/Syndrome of Kidney Yang Deficiency/Impotence/Animal Model引用本文复制引用
张宗保..鹿茸益肾胶囊治疗肾阳虚证阳痿的药效学研究[J].中国执业药师,2014,(6):20-23,4.基金项目
济宁市科技发展计划项目（[2010]第27号），山东省保健科学技术奖获奖项目 （）
